Reversing Skin Aging: The Science Behind Peptides with Alessandra, Chief Scientific Officer of OneSkin

Is your skincare actually working? Or are you just throwing money at products that don’t deliver?

In this episode of Midlife Conversations, I share the raw truth about my skin at 53. Despite trying all the things—creams, treatments, you name it—I’m still navigating the changes that come with aging skin. But here’s the good news…

I brought in Alessandra, the Chief Scientific Officer of OneSkin, to uncover something game-changing. What’s the real deal with the OS-O1 peptide everyone’s talking about? Can it really tackle skin aging at the root? And why is inflammation such a big player in this story?

Alessandra’s journey from Brazil to founding OneSkin is just as fascinating as the science behind this revolutionary peptide. We’re diving into collagen, inflammation, and how to make your skincare routine actually work for you.

Reversing Skin Aging: The Science Behind Peptides with Alessandra, Lead Scientist at OneSkin pin

Want to know when to use these products? Or if they’re really worth it? Listen in!

How Did OneSkin Come to Play? 

With a background in stem cell biology and wound healing, a team of women founded OneSkin. Their goal was to innovate and build on what REALLY works when it comes to anti-aging skincare. Prior to OneSkin, the gold standard of skincare were ingredients like retinoids and hydroquinone that were originally founded in the 50s, were claimed to be healthy, but they were not designed to address root causes of skin aging below the surface. 

In addition to those ingredients being hard on your liver, they can also cause irritation and sensitivity in their process – AND – they’re not even SOLVING the aging skin issue. This is where OneSkin shines apart from the “competition”. 

The OneSkin Topical Peptide Difference 

OneSkin is a topical peptide. I know we have heard that topicals do not work and that they must be ingested. However, when you ingest things like collagen, for example, while it can help minimize the appearance of SOME fine lines, the benefits are not targeted JUST to the skin. 

When you apply a topical peptide, it is acting directly ON the skin. OS-01, OneSkin’s proprietary patented peptide, is the first ingredient scientifically proven to reverse skin’s biological age. 

As we age, we get collagen breakdown, produce less collagen, get sagging, and hyperpigmentation. We start accumulating damaged cells that contribute to dysfunction tissue. Prior to OneSkin, products don’t target these dead “zombie” cells in the skin. 

After testing over 900 molecules, OneSkin found a molecule that reduced the burden caused by the zombie cells, reduced the accumulation of them, and leaves you with less of what is driving aging from the root cause. 

The OS-01 peptide improves DNA repair, increases skin function, produces more collagen, stronger barrier, smoother skin, more firm skin, and improvement of skin elasticity. 

How Long Does It Take for OS-01 To Make a Difference? 

From clinical studies there has been proven significant improvements in elasticity, firmness, and hydration within 3 months. I personally experience these improvements and I am only at month two of using these products! 

  • 95.5% of participants saw improved skin evenness, radiance, pores and firmness*
  • 87% of participants saw a reduction in the appearance of fine lines & wrinkles*
  • 100% of participants saw improved skin smoothness and overall appearance*
  • Participants skin’s barrier function improved by an average of + 15%*

*Shown in a 12-week clinical study performed by a third party research organization with 22 participants (OneSkin manuscript in process of publication)

How to Use OneSkin 

Ideally you start to use OneSkin when you first start seeing the signs of aging in your skin. The earlier you start is great – preventing is always better than reversing. BUT, even if you already have signs, it can still HELP avoid further damage later on. 

The way that OneSkin works best is to use the entire system. However, even if you just added one product from OneSkin that has the peptide, it will still make a difference! 

The OneSkin product should be applied first on clean skin for maximum absorption. OneSkin is a super safe product to use, but still be sure to not apply on damaged skin with open wounds. 

More Tips for Great Skin

  • Simplify your skincare routine and use great skincare products
  • Stay hydrated with clean water and minerals 
  • Exercise daily 
  • Eat healthy foods, avoid added sugars and processed foods 
  • Prioritize getting good sleep 

This and more in this episode! Give it a listen! 

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Posted by Midlife Conversations with Natalie Jill

I help simplify complicated health topics for MIDLIFE women so you can OPTIMIZE aging and thrive at any age!